BDBM297345 N-(6-((1-oxoisoindolin-5-yl)amino)pyrimidin-4-yl)cyclopropanecarboxamide (Cpd. No. 12)::US10112955, Example 12

SMILES O=C(Nc1cc(Nc2ccc3C(=O)NCc3c2)ncn1)C1CC1

InChI Key InChIKey=MIVZVCNGBMCBAA-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 297345   

TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
A*Star

Curated by ChEMBL
LigandPNGBDBM297345(N-(6-((1-oxoisoindolin-5-yl)amino)pyrimidin-4-yl)c...)
Affinity DataIC50:  430nMAssay Description:Inhibition of phosphorylation of eIF4E (unknown origin) in HCT-116 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed